Application Note                                                                                              Zaptron Systems, Inc.

Enhance Yield of Synthetic Drug – Sulfonamide

Goal:

Increase the yield of sulfonamide production – synthetic method. Synthetic drugs, such as sulfonamide, usually have long flow-chart of synthesis, leading to relatively low production yield often times. Therefore mathematical optimization may bring about great economic benefit to drug manufacturers.

Objective:

Enhance the yield of sulfonamide

Features influencing sulfonamide yield:

 

Result:

MasterMiner was used to analyze the yield data obtained from synthetic drug production. Very good regularity (data pattern) was found in the raw data, which led to a very accurate model for the manufacturing process. After optimization, sulfonamide yield was increased significantly.

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